SS-31 (Elamipretide) · CAS 736992-21-5
SS-31 10mg
SS-31 (Elamipretide, MTP-131) is a mitochondria-targeted tetrapeptide that binds cardiolipin in the inner mitochondrial membrane. Restores ATP synthesis in aged and ischemic models. Phase 2 clinical data in heart failure and Barth syndrome. 98.9% HPLC purity.
Shop This CompoundFor laboratory research use only. Not for human consumption. Not FDA-approved for any use.
Compound Data Sheet — SS-31 10mg
- Vial Size
- 10mg
- Form
- Lyophilized Powder
- Purity
- 98.9% HPLC
- CAS
- 736992-21-5
- Storage
- -20C long-term
Common Researcher Questions — SS-31 10mg
What is the mechanism of SS-31 in aging research?+
Mitochondrial dysfunction in aging involves cardiolipin oxidation that disrupts electron transport chain supercomplexes. SS-31 binds and protects cardiolipin, reversing this dysfunction to restore ATP output in aged cell models.
Mechanism of Action — SS-31 (Elamipretide)
Cardiolipin stabilization in the inner mitochondrial membrane preserves electron transport chain supercomplex organization (Complex I/III/IV), reducing electron leak, ROS generation, and restoring ATP production efficiency.
